Anyone ever despise a character so much that your feelings of disdain carried over (to some degree) toward the actor who played the character?

My personal example of this is Catherine Keener, whose character in Being John Malkovich I found to be so incredibly grating that I got to the point where I'm instinctively inclined to dislike her whenever she pops up. Completely unfounded, I realize. I suppose the flip side of this speaks to just how well the actress/actor played the part in question.

It's an interesting phenomenon. There was a great Op-Ed piece in the NY Times back in 2013, by Anna Gunn, talking about how many Breaking Bad fans hated Skyler White so much (for not siding with Walt, the show's protagonist) that the feelings contempt for the character were actually felt by her real world persona.